PI: Porntipa Korprasertthaworn
Lab location: Pr 521, Department of Pharmacology
Contact: 02-201-5650; porntipa.kor@mahidol.ac.th
Research focus
The current research is now focusing on drug and xenobiotic metabolism in vitro and developing in vitro-in vivo extrapolation approach. The study includes characterization the impact of drug-drug and drug-herb interactions on drug safety and efficacy.
Selected publications
- Korprasertthaworn P, Chau N, Nair PC, Rowland A, Miners
JO. Inhibition of human UDP-glucuronosyltransferase (UGT)
enzymes by kinase inhibitors: Effects of dabrafenib,
ibrutinib, nintedanib, trametinib and BIBF 1202. Biochem
Pharmacol. 2019;169:113616. - Korprasertthaworn P, Polasek TM, Sorich MJ, McLachlan
AJ, Miners JO, Tucker GT, et al. In vitro characterization of
human liver microsomal kinetics and enzyme involvement
in olanzapine metabolism. Drug Metab Dispos. 2015;43
(11):1806-14.
