PI: Amornrat N. Jensen
Lab location: PR107, Department of Pathobiology
Contact: 02-201-5553, amornrat.nar@mahidol.edu
Research focus
Our laboratory’s mission is to apply knowledge drawn from using model system to understand the molecular pathology of diseases as well as molecular mechanisms of drug treatment. The ultimate goal is to search for novel therapeutic strategies in various areas including
- Targeted therapy for genetic diseases
- Synergistic drugs for malaria
- Novel anti-cancer agents
- Novel anti-aging compounds
Selected publications
- Pongwattanakewin O, Phyu T, Suesattayapirom S, Jensen LT, Jensen AN*. Possible Role of the Ca(2+)/Mn(2+) P-Type ATPase Pmr1p on Artemisinin Toxicity through an Induction of Intracellular Oxidative Stress. Molecules. 2019;24(7).
- Jensen LT, Phyu T, Jain A, Kaewwanna C, Jensen AN*. Decreased accumulation of superoxide dismutase 2 within mitochondria in the yeast model of Shwachman-Diamond syndrome. J Cell Biochem. 2019;120(8):13867-80.
- Van Voorhis WC, Adams JH, Adelfio R, Ahyong V, Akabas MH, Alano P, et al. Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond. PLoS Pathog. 2016;12(7):e1005763.
- Kanprasoet W, Jensen LT, Sriprach S, Thitiananpakorn K, Rattanapornsompong K, Jensen AN*. Deletion of Mitochondrial Porin Alleviates Stress Sensitivity in the Yeast Model of Shwachman-Diamond Syndrome. J Genet Genomics. 2015;42(12):671-84.
